Question about MC-11 Adapter Canon EF to Sony E - 306480

If a general answer is expected: No.
It is possible that individual EF-S lenses will work, but no one can guarantee that. Sigma officially only supports its own lenses of the newer series with EF mount. Sigma itself does not build EF-S lenses. And in general about Canon EF lenses on the Sigma MC-11: They can work great, not so great or not at all. This is a combination that no one supports.